Severe Weight Loss - Linked to Higher Risk in Study of Patients

Weight loss at the time of diagnosis appears common among people with amyotrophic lateral sclerosis (ALS), regardless of whether they have dysphagia or other bulbar-onset symptoms, a study looking at more than 2,400 patients found.

A severe degree of weight loss is associated with a higher risk of death, its researchers reported, indicating that body weight may be an important prognostic factor of survival. Care to avoid a sudden drop in weight may need to be tailored to the individual.

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